Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
TBXAS1 P24557 thromboxane A synthase 1 1.4E-20 0.619 0.615 12
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 17
SMAD1 Q15797 SMAD family member 1 Transcription factor 0.99 0.533 0.731 6
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885 48
RNLS Q5VYX0 renalase, FAD dependent amine oxidase 3.8E-06 0.678 0.423 6
RGS2 P41220 regulator of G protein signaling 2 Enzyme modulator 5.7E-06 0.561 0.769 7
PTAFR P25105 platelet activating factor receptor G-protein coupled receptor 0.24 0.575 0.731 17
PRF1 P14222 perforin 1 5.5E-06 0.540 0.692 7
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885 37
PLEKHA7 Q6IQ23 pleckstrin homology domain containing A7 6.2E-09 0.729 0.423 3
PDGFD Q9GZP0 platelet derived growth factor D Signaling 1.7E-03 0.579 0.538 6
PDGFB P01127 platelet derived growth factor subunit B Signaling 0.77 0.488 0.846 17
MS4A1 P11836 membrane spanning 4-domains A1 Receptor 5.1E-05 0.411 0.846 1
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 86
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885 24
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885 27
LTC4S Q16873 leukotriene C4 synthase Enzyme 8.5E-04 0.647 0.731 4
LTBP1 Q14766 latent transforming growth factor beta binding protein 1 Calcium-binding protein 3.7E-09 0.670 0.500 3
ITGB3 P05106 integrin subunit beta 3 Receptor 1.7E-03 0.485 0.846 13
ITGB1 P05556 integrin subunit beta 1 Receptor 0.98 0.496 0.808 6
ITGA3 P26006 integrin subunit alpha 3 3.6E-07 0.573 0.731 5
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 92
GJA5 P36382 gap junction protein alpha 5 Cell-cell junction 1.8E-02 0.575 0.577 11
GAS6 Q14393 growth arrest specific 6 Extracellular structure 3.4E-02 0.500 0.769 2